数据分析

脑海科技数据分析服务之方案1

发布日期:2022-05-17 14:12 浏览次数:

 

 

 

Introduction

 

After preprocessing, the time series for each voxel was filtered (bandpass, 0.01-0.08 Hz) to removethe effects of very-low-frequency drift and high frequency noise, e.g., respiratory and heart rhythms. Next, the filtered time series was transformedto a frequency domain with a fast Fourier transform (FFT) (parameters: taperpercent=0, FFT length=shortest) and the power spectrum was then obtained. Sincethe power of a given frequency is proportional to the square of the amplitudeof this frequency component of the original time series in the time domain, thesquare root was calculated at each frequency of the power spectrum and theaveraged square root was obtained across 0.01-0.08 Hz at each voxel. Thisaveraged square root was taken as the ALFF. (Zang et al., 2007)

 

Process Stream

 

part 1

Data quality control

part 2

Preprocessing

1. Remove first N time points

2. Slice timing correction

3. Motion correction

4. Spatial normalization

5. Spatial smoothing

6. Detrend

7. Nuisance regression

 

Approach

ALFF (conventional) calculation

 

Statistical Analysis

Statistical modeling (group): 

two-sample t-test/paired t-test…

Statistical inference (group): 

FDR/GRF…

 

Correlation Analysis

ALFF and clinical variables

 

part 3

 


Reporting and visualizing


Example 1
 


 




 

Liu et al., 2020
 

 

Example 2

 


 

 

Hui et al., 2020

 

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